Mole removal cost The price of mole removal depends on the size, shape and location and the complexity of the procedure. Some dermatologists charge $125.00 and excisions at $250.00. Most are more expensive. For instance, a very small mole in an area that is not cosmetically sensitive can be removed simply and without sutures whereas a mole that is larger and deeper will require more work such as layered closure with sutures. There are two ways to remove a mole, and they differ in price. Shaving a mole means cutting it off at the skin’s surface. The area usually scabs over for a week or so.